- Spiegelman, B.M. (2013) Banting Lecture 2012: Regulation of adipogenesis: toward new therapeutics for metabolic disease. Diabetes, 62, 1774-1782.
- Lidell, M.E., Betz, M.J. and Enerback, S. (2014) Brown adipose tissue and its therapeutic potential. J Intern Med, 276, 364-377.
- Steinberg, G.R. (2018) Cellular Energy Sensing and Metabolism-Implications for Treating Diabetes: The 2017 Outstanding Scientific Achievement Award Lecture. Diabetes, 67, 169-179.
- Herz, C.T. and Kiefer, F.W. (2019) Adipose tissue browning in mice and humans. J Endocrinol, 241, R97-R109.
- Lee, P., Swarbrick, M.M. and Ho, K.K. (2013) Brown adipose tissue in adult humans: a metabolic renaissance. Endocr Rev, 34, 413-438.
- Kaisanlahti, A. and Glumoff, T. (2019) Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes. J Physiol Biochem, 75, 1-10.
- Yoneshiro, T. and Saito, M. (2015) Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans. Ann Med, 47, 133-141.
- Lee, M.W., Lee, M. and Oh, K.J. (2019) Adipose Tissue-Derived Signatures for Obesity and Type 2 Diabetes: Adipokines, Batokines and MicroRNAs. J Clin Med, 8.
- Zhang, B., Yang, Y., Xiang, L., Zhao, Z. and Ye, R. (2019) Adipose-derived exosomes: A novel adipokine in obesity-associated diabetes. J Cell Physiol.
- Hanna, J., Hossain, G.S. and Kocerha, J. (2019) The Potential for microRNA Therapeutics and Clinical Research. Front Genet, 10, 478.
- Ying, W., Riopel, M., Bandyopadhyay, G., Dong, Y., Birmingham, A., Seo, J.B., Ofrecio, J.M., Wollam, J., Hernandez-Carretero, A., Fu, W. et al. (2017) Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. Cell, 171, 372-384 e312.
- Pan, Y., Hui, X., Hoo, R.L.C., Ye, D., Chan, C.Y.C., Feng, T., Wang, Y., Lam, K.S.L. and Xu, A. (2019) Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation. J Clin Invest, 129, 834-849.
- Li, Z. and Rana, T.M. (2014) Therapeutic targeting of microRNAs: current status and future challenges. Nat Rev Drug Discov, 13, 622-638.
- Smith, CIE, Zain, R. Therapeutic Oligonucleotides: State of the Art. Annu Rev Pharmacol Toxicol. 2019;59:605-630.
- Hanna J, Hossain GS, Kocerha J. The Potential for microRNA Therapeutics and Clinical Research. Front Genet. 2019;10:478.
- Bennett, C.F. Therapeutic Antisense Oligonucleotides are coming of Age. Annual Review of Medicine. 2019 Jan 27;70:307-321.
- Levin, A.A. Treating disease at the RNA level with oligonucleotides. New Engl. J. Med. 2019 Jan 3;380(1):57-70: PMID: 30601736
- Crooke, S.T., X. H. Liang, B. F. Baker and R. M. Crooke. Antisense technology: a review. J Biol Chem. 2021 Feb 15; PMID: 33600796.
- Crooke, S. T., Baker, B. F., Crooke, R. M., Liang, X. H. Antisense technology: an overview and prospectus. Nat Rev Drug Discov. 2021; PMID: 33762737.
challenges and opportunities. EMBO Mol Med. 2021. PMID: 33821570.
Delivery of oligonucleotide-based therapeutics:- Lheureux, S., M. Braunstein, and A.M. Oza, Epithelial Ovarian Cancer: Evolution of management in the era of precision medicine. CA Cancer J Clin, 2019. 69(4): p. 280-304.
- Talhouk, A., et al., Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE). Clin Cancer Res, 2020. 26(20): p. 5411-5423.
- Pascual-Anton, L., et al., Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer. Int J Mol Sci, 2021. 22(21).
- Yoshida, K., et al., The clinical impact of intra- and extracellular miRNAs in Ovarian Cancer. Cancer Sci, 2020. 111(10): p. 3435-3444.
- Deb, B., A. Uddin, and S. Chakraborty, miRNAs and Ovarian Cancer: An overview. J Cell Physiol, 2018. 233(5): p. 3846-3854.
- Mirahmadi, Y., et al., MicroRNAs as Biomarkers for Early Diagnosis, Prognosis, and Therapeutic Targeting of Ovarian Cancer. J Oncol, 2021. 2021: p. 3408937.
- Croft, P.K., et al., Ovarian-Cancer-Associated Extracellular Vesicles: Microenvironmental Regulation and Potential Clinical Applications. Cells, 2021. 10(9).
- Liang, Z., et al., Targeting Membrane Receptors of Ovarian Cancer Cells for Therapy. Curr Cancer Drug Targets, 2019. 19(6): p. 449-467.
- Wallace-Povirk, A., et al., Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer. Cancers (Basel), 2021. 14(1).
- Martin-Sabroso, C., et al., Active Targeted Nanoformulations via Folate Receptors: State of the Art and Future Perspectives. Pharmaceutics, 2021. 14(1).
- Nieman, K.M., et al., Adipocytes promote Ovarian Cancer metastasis and provide energy for rapid tumor growth. Nat Med, 2011. 17(11): p. 1498-503.
- Motohara, T., et al., An evolving story of the metastatic voyage of Ovarian Cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment. Oncogene, 2019. 38(16): p. 2885-2898.
- Iyoshi, S., et al., Pro-tumoral behavior of omental adipocyte-derived fibroblasts in tumor microenvironment at the metastatic site of Ovarian Cancer. Int J Cancer, 2021. 149(11): p. 1961-1972.
- Mukherjee, A., et al., Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance. Cancer Res, 2020. 80(8): p. 1748-1761.
- Gharpure, K.M., et al., FABP4 as a key determinant of metastatic potential of Ovarian Cancer. Nat Commun, 2018. 9(1): p. 2923.
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